QTRT1 Antibody
Product Sizes
50ug
£305.00
OACA06393-50UG
100ug
£463.00
OACA06393-100UG
About this Product
- SKU:
- OACA06393
- Additional Names:
- FP3235;guanine insertion enzyme;queuine tRNA-ribosyltransferase 1;queuine tRNA-ribosyltransferase catalytic subunit 1;TGT;TGT; 43-KD subunit;TGT; catalytic subunit;TGUT;tRNA-guanine transglycosylase.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp; -Asn; -His and -Tyr); resulting in the hypermodified nucleoside queuosine (7-(((4;5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023; PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA; forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine; allowing a nucleophilic attack on the C1' of the ribose to form the product (By similarity).
- Gene Details:
- queuine tRNA-ribosyltransferase catalytic subunit 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)
- Isotype:
- IgG
- Protein Details:
- Queuine tRNA-ribosyltransferase catalytic subunit 1
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
