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Antibodies

DPH1 Antibody

Product Sizes
50ug
£305.00
OACA06116-50UG
100ug
£463.00
OACA06116-100UG
About this Product
SKU:
OACA06116
Additional Names:
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1;candidate tumor suppressor in ovarian cancer 1;DEDSSH;diphthamide biosynthesis protein 1;diphthamide biosynthesis protein 2 homolog-like 1;diphtheria toxin resistance protein 1;diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1;DPH1 homolog;DPH2L;DPH2L1;DPH2-like 1;DPH-like 1;ovarian cancer-associated gene 1 protein;ovarian tumor suppressor candidate 1;OVCA1;S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Required for the first step in the synthesis of diphthamide; a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). When overexpressed; suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers (By similarity). Plays a role in embryonic growth; organogenesis and postnatal survival (By similarity).
Gene Details:
diphthamide biosynthesis 1
Host:
Rabbit
Immunogen:
Recombinant Human 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 protein (192-318AA)
Isotype:
IgG
Protein Details:
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody