POLR3E Antibody
Product Sizes
50ug
£305.00
OACA06081-50UG
100ug
£463.00
OACA06081-100UG
About this Product
- SKU:
- OACA06081
- Additional Names:
- C37;DNA-directed RNA polymerase III 80 kDa polypeptide;DNA-directed RNA polymerase III subunit RPC5;polymerase (RNA) III (DNA directed) polypeptide E (80kD);polymerase (RNA) III subunit E;RNA polymerase III 80 kDa subunit RPC5;RNA polymerase III subunit C5;RPC5;SIN.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs; such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts; such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
- Gene Details:
- RNA polymerase III subunit E
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA-directed RNA polymerase III subunit RPC5 protein (1-260AA)
- Isotype:
- IgG
- Protein Details:
- DNA-directed RNA polymerase III subunit RPC5
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
