DCUN1D1 Antibody
Product Sizes
50ug
£305.00
OACA05541-50UG
100ug
£463.00
OACA05541-100UG
About this Product
- SKU:
- OACA05541
- Additional Names:
- DCN1; defective in cullin neddylation 1; domain containing 1;DCN1-like protein 1;DCNL1;DCUN1 domain-containing protein 1;DCUN1L1;defective in cullin neddylation protein 1-like protein 1;RP42;RP42 homolog;SCCRO;SCRO;squamous cell carcinoma-related oncogene;Tes3.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation; enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8) thioester to the complex; and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity (PubMed:25349211; PubMed:28581483). Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity).
- Gene Details:
- defective in cullin neddylation 1 domain containing 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DCN1-like protein 1 protein (1-259AA)
- Isotype:
- IgG
- Protein Details:
- DCN1-like protein 1
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
