DDX42 Antibody
Product Sizes
50ug
£305.00
OACA05217-50UG
100ug
£463.00
OACA05217-100UG
About this Product
- SKU:
- OACA05217
- Additional Names:
- ATP-dependent RNA helicase DDX42;DDX42P;DEAD (Asp-Glu-Ala-Asp) box helicase 42;DEAD (Asp-Glu-Ala-Asp) box polypeptide 42;DEAD box protein 42;RHELP;RNA helicase-like protein;RNA helicase-related protein;RNAHP;SF3b DEAD box protein;SF3b125;SF3B8;splicing factor 3b; subunit 8;splicing factor 3B-associated 125 kDa protein.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation; whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.
- Gene Details:
- DEAD-box helicase 42
- Host:
- Rabbit
- Immunogen:
- Recombinant Human ATP-dependent RNA helicase DDX42 protein (519-819AA)
- Isotype:
- IgG
- Protein Details:
- ATP-dependent RNA helicase DDX42
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
