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Antibodies

SMG6 Antibody

Product Sizes
50ug
£305.00
OACA05213-50UG
100ug
£463.00
OACA05213-100UG
About this Product
SKU:
OACA05213
Additional Names:
C17orf31;EST1 telomerase component homolog A;EST1A;EST1-like protein A;ever shorter telomeres 1A;hSMG5/7a;SMG-6;Smg-6 homolog;smg-6 homolog; nonsense mediated mRNA decay factor;telomerase subunit EST1A;telomerase-binding protein EST1A.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping; chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA; but not to a telomerase RNA template component (TER).
Gene Details:
SMG6 nonsense mediated mRNA decay factor
Host:
Rabbit
Immunogen:
Recombinant Human Telomerase-binding protein EST1A protein (251-511AA)
Isotype:
IgG
Protein Details:
Telomerase-binding protein EST1A
Purity:
>95%
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody