MAPRE1 Antibody
Product Sizes
50ug
£305.00
OACA04763-50UG
100ug
£463.00
OACA04763-100UG
About this Product
- SKU:
- OACA04763
- Additional Names:
- adenomatous polyposis coli-binding protein EB1;APC-binding protein EB1;EB1;end-binding protein 1;microtubule-associated protein RP/EB family member 1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton (PubMed:12388762; PubMed:16109370; PubMed:19632184; PubMed:21646404; PubMed:28726242; PubMed:28814570). Promotes cytoplasmic microtubule nucleation and elongation (PubMed:12388762; PubMed:16109370; PubMed:19632184; PubMed:21646404; PubMed:28726242; PubMed:28814570). May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes (PubMed:12388762). Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP; leading to recruit CAMSAP2 to the Golgi apparatus; thereby tethering non-centrosomal minus-end microtubules to the Golgi; an important step for polarized cell movement (PubMed:28814570). Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (PubMed:28814570). Acts as a regulator of autophagosome transport via interaction with CAMSAP2 (PubMed:28726242). May play a role in cell migration (By similarity).
- Gene Details:
- microtubule associated protein RP/EB family member 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Microtubule-associated protein RP/EB family member 1 protein (2-268AA)
- Isotype:
- IgG
- Protein Details:
- Microtubule-associated protein RP/EB family member 1
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
