ARL6IP1 Antibody
Product Sizes
50ug
£305.00
OACA04713-50UG
100ug
£463.00
OACA04713-100UG
About this Product
- SKU:
- OACA04713
- Additional Names:
- ADP-ribosylation factor GTPase 6 interacting protein 1;ADP-ribosylation factor-like 6 interacting protein 1;ADP-ribosylation factor-like protein 6-interacting protein 1;aip-1;AIP1;apoptotic regulator in the membrane of the endoplasmic reticulum;ARL-6-interacting protein 1;ARL6IP;ARMER;SPG61.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity-dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5; a negative regulator of SLC1A1/EAAC1-mediated glutamate transport (By similarity). Plays a role in the formation and stabilization of endoplasmic reticulum tubules (PubMed:24262037). Negatively regulates apoptosis; possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates and downstream markers of apoptosis but not CASP9 itself (PubMed:12754298). May be involved in protein transport; membrane trafficking; or cell signaling during hematopoietic maturation (PubMed:10995579).
- Gene Details:
- ADP ribosylation factor like GTPase 6 interacting protein 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human ADP-ribosylation factor-like protein 6-interacting protein 1 protein (93-133AA)
- Isotype:
- IgG
- Protein Details:
- ADP-ribosylation factor-like protein 6-interacting protein 1
- Purity:
- >95%
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
