ATG5 Antibody
Product Sizes
50ug
£305.00
OACA04319-50UG
100ug
£463.00
OACA04319-100UG
About this Product
- SKU:
- OACA04319
- Additional Names:
- APG5;APG5 autophagy 5-like;APG5L;APG5-LIKE;apoptosis-specific protein;ASP;ATG5 autophagy related 5 homolog;autophagy protein 5;hAPG5;SCAR25.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Involved in autophagic vesicle formation. Conjugation with ATG12; through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme; is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage; and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures; as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
- Gene Details:
- autophagy related 5
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Autophagy protein 5 protein (5-272AA)
- Isotype:
- IgG
- Protein Details:
- Autophagy protein 5
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
