SIRPA Antibody
Product Sizes
50ug
£305.00
OACA03670-50UG
100ug
£463.00
OACA03670-100UG
About this Product
- SKU:
- OACA03670
- Additional Names:
- BIT;Brain Ig-like molecule with tyrosine-based activation motifs;brain-immunoglobulin-like molecule with tyrosine-based activation motifs;CD172 antigen-like family member A;CD172A;inhibitory receptor SHPS-1;macrophage fusion receptor;MFR;MYD-1;myd-1 antigen;P84;PTPNS1;SHPS1;Signal-regulatory protein alpha-1;Signal-regulatory protein alpha-2;Signal-regulatory protein alpha-3;SIRP;tyrosine phosphatase SHP substrate 1;tyrosine-protein phosphatase non-receptor type substrate 1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6; PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons; neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion; growth factors or insulin. Mediates negative regulation of phagocytosis; mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.
- Gene Details:
- signal regulatory protein alpha
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Tyrosine-protein phosphatase non-receptor type substrate 1 protein (31-373AA)
- Isotype:
- IgG
- Protein Details:
- Tyrosine-protein phosphatase non-receptor type substrate 1
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
