PLA2G16 Antibody
Product Sizes
50ug
£305.00
OACA03451-50UG
100ug
£463.00
OACA03451-100UG
About this Product
- SKU:
- OACA03451
- Additional Names:
- adipose-specific phospholipase A2;adipose-specific PLA2;AdPLA;Ca-independent phospholipase A1/2;group XVI phospholipase A1/A2;group XVI phospholipase A2;HRAS-like suppressor 1;HRAS-like suppressor 3;HRASLS3;H-rev 107 protein homolog;HREV107;H-REV107;HREV107-1;H-REV107-1;HREV107-3;HRSL3;phospholipase A and acyltransferase 3;phospholipase A/acyltransferase-3;phospholipase A2 group XVI;PLA2G16;PLAAT-3;renal carcinoma antigen NY-REN-65.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- Varies by lot. See vial for exact concentration.
- Extra Details:
- Lipid-modifying enzyme that acts as major regulator of adipocyte lipolysis by catalyzing the release of fatty acids from phospholipids in adipose tissue (PubMed:19615464; PubMed:19047760; PubMed:20837014; PubMed:22605381; PubMed:22923616). Shows phospholipase A1 and A2 activity; catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE) (PubMed:19615464; PubMed:19047760; PubMed:20837014; PubMed:22605381; PubMed:22923616). For most substrates; phospholipase A1 activity is much higher than phospholipase A2 activity (PubMed:19047760). Phospholipase activity causes decreased intracellular levels of ether-type lipids; affecting peroxisome metabolism (By similarity). May also have acyltransferase activity: catalyzes both N-acylation of phosphatidylethanolamine to form N-acyl-phosphatidylethanolamine and O-acylation of lyso-phosphatidylcholines to form phosphatidylcholines (PubMed:22605381; PubMed:25383759). The relevance of acyltransferase activity in vivo is however unclear and would require additional evidences (PubMed:22605381; PubMed:25383759). Also has weak lysophospholipase activity (By similarity).
- Gene Details:
- phospholipase A and acyltransferase 3
- Host:
- Rabbit
- Immunogen:
- Recombinant Human HRAS-like suppressor 3 protein (1-132AA)
- Isotype:
- IgG
- Protein Details:
- HRAS-like suppressor 3
- Purity:
- > 95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
