PHF10 Antibody
Product Sizes
50ug
£305.00
OACA03440-50UG
100ug
£463.00
OACA03440-100UG
About this Product
- SKU:
- OACA03440
- Additional Names:
- BAF45A;BRG1-associated factor 45a;BRG1-associated factor; 45-KD; A;PHD finger protein 10;PHD zinc finger protein XAP135;SMARCG4;XAP135.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons; npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A; are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
- Gene Details:
- PHD finger protein 10
- Host:
- Rabbit
- Immunogen:
- Recombinant Human PHD finger protein 10 protein (151-360AA)
- Isotype:
- IgG
- Protein Details:
- PHD finger protein 10
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
