DNAJB2 Antibody
Product Sizes
50ug
£305.00
OACA02863-50UG
100ug
£463.00
OACA02863-100UG
About this Product
- SKU:
- OACA02863
- Additional Names:
- CMT2T;DnaJ (Hsp40) homolog; subfamily B; member 2;dnaJ homolog subfamily B member 2;dnaJ protein homolog 1;DSMA5;heat shock 40 kDa protein 3;heat shock protein J1;heat shock protein; neuronal DNAJ-like 1;HSJ1;HSJ-1;HSPF3.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Functions as a co-chaperone; regulating the substrate binding and activating the ATPase activity of chaperones of the HSP70/heat shock protein 70 family (PubMed:7957263; PubMed:22219199). In parallel; also contributes to the ubiquitin-dependent proteasomal degradation of misfolded proteins (PubMed:15936278; PubMed:21625540). Thereby; may regulate the aggregation and promote the functional recovery of misfolded proteins like HTT; MC4R; PRKN; RHO and SOD1 and be crucial for many biological processes (PubMed:12754272; PubMed:20889486; PubMed:21719532; PubMed:22396390; PubMed:24023695). Isoform 1 which is localized to the endoplasmic reticulum membranes may specifically function in ER-associated protein degradation of misfolded proteins (PubMed:15936278).
- Gene Details:
- DnaJ heat shock protein family (Hsp40) member B2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DnaJ homolog subfamily B member 2 protein (2-324AA)
- Isotype:
- IgG
- Protein Details:
- DnaJ homolog subfamily B member 2
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
