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Antibodies

CFLAR Antibody

Product Sizes
50ug
£305.00
OACA02741-50UG
100ug
£463.00
OACA02741-100UG
About this Product
SKU:
OACA02741
Additional Names:
CASH;CASP8 and FADD-like apoptosis regulator;CASP8AP1;caspase homolog;caspase-eight-related protein;caspase-like apoptosis regulatory protein;caspase-related inducer of apoptosis;Casper;cellular FLICE-like inhibitory protein;cFLIP;c-FLIP;c-FLIPL;c-FLIPR;c-FLIPS;CLARP;FADD-like antiapoptotic molecule 1;FLAME;FLAME1;FLAME-1;FLIP;I-FLICE;inhibitor of FLICE;MACH-related inducer of toxicity;MRIT;testis secretory sperm-binding protein Li 233m;Usurpin;usurpin beta.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Gene Details:
CASP8 and FADD like apoptosis regulator
Host:
Rabbit
Immunogen:
Recombinant Human CASP8 and FADD-like apoptosis regulator protein (1-250AA)
Isotype:
IgG
Protein Details:
CASP8 and FADD-like apoptosis regulator
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody