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Antibodies

CD46 Antibody

Product Sizes
50ug
£305.00
OACA02716-50UG
100ug
£463.00
OACA02716-100UG
About this Product
SKU:
OACA02716
Additional Names:
AHUS2;antigen identified by monoclonal antibody TRA-2-10;CD46 antigen; complement regulatory protein;CD46 molecule; complement regulatory protein;complement membrane cofactor protein;MCP;measles virus receptor;membrane cofactor protein;membrane cofactor protein (CD46; trophoblast-lymphocyte cross-reactive antigen);MIC10;TLX;TRA2.10;trophoblast leucocyte common antigen;trophoblast leukocyte common antigen;trophoblast-lymphocyte cross-reactive antigen.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Acts as a cofactor for complement factor I; a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10; and therefore are thought to prevent autoimmunity.
Gene Details:
CD46 molecule
Host:
Rabbit
Immunogen:
Recombinant Human Membrane cofactor protein (164-325AA)
Isotype:
IgG
Protein Details:
Membrane cofactor protein
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody