STK24 Antibody
Product Sizes
50ug
£305.00
OACA02639-50UG
100ug
£463.00
OACA02639-100UG
About this Product
- SKU:
- OACA02639
- Additional Names:
- epididymis secretory protein Li 95;HEL-S-95;mammalian STE20-like protein kinase 3;MST3;MST3B;serine/threonine kinase 24 (STE20 homolog; yeast);serine/threonine-protein kinase 24;STE20;STE20-like kinase 3;STE20-like kinase MST3;sterile 20-like kinase 3;STK3.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9); p38 (MAPK11; MAPK12; MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006). Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
- Gene Details:
- serine/threonine kinase 24
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Serine/threonine-protein kinase 24 protein (1-431AA)
- Isotype:
- IgG
- Protein Details:
- Serine/threonine-protein kinase 24
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
