ASAH2 Antibody
Product Sizes
50ug
£305.00
OACA02612-50UG
100ug
£463.00
OACA02612-100UG
About this Product
- SKU:
- OACA02612
- Additional Names:
- acylsphingosine deacylase 2;BCDase;HNAC1;LCDase;mitochondrial ceramidase;N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2;N-acylsphingosine amidohydrolase 2;NCDase;N-CDase;neutral ceramidase;neutral/alkaline ceramidase;non-lysosomal ceramidase.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5 (PubMed:10781606; PubMed:26190575). Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide; thereby preventing ceramide-induced apoptosis; and generating sphingosine; a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
- Gene Details:
- N-acylsphingosine amidohydrolase 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Neutral ceramidase protein (255-506AA)
- Isotype:
- IgG
- Protein Details:
- Neutral ceramidase
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
