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Antibodies

APLNR Antibody

Product Sizes
50ug
£305.00
OACA02590-50UG
100ug
£463.00
OACA02590-100UG
About this Product
SKU:
OACA02590
Additional Names:
AGTRL1;angiotensin II receptor-like 1;angiotensin receptor-like 1;apelin receptor;APJ;APJ (apelin) receptor;APJ receptor;APJR;G protein-coupled receptor APJ;G-protein coupled receptor APJ;G-protein coupled receptor HG11;HG11;HG11 orphan receptor.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:11090199; PubMed:25639753; PubMed:28137936). Plays a key role in early development such as gastrulation; blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone (By similarity). May promote angioblast migration toward the embryonic midline; i.e. the position of the future vessel formation; during vasculogenesis (By similarity). Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development (By similarity). Plays also a role in various processes in adults such as regulation of blood vessel formation; blood pressure; heart contractility and heart failure (PubMed:25639753; PubMed:28137936).
Gene Details:
apelin receptor
Host:
Rabbit
Immunogen:
Recombinant Human Apelin receptor protein (309-380AA)
Isotype:
IgG
Protein Details:
Apelin receptor
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody