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Antibodies

APLN Antibody

Product Sizes
50ug
£305.00
OACA02588-50UG
100ug
£463.00
OACA02588-100UG
About this Product
SKU:
OACA02588
Additional Names:
AGTRL1 ligand;APEL;apelin;APJ endogenous ligand;XNPEP2.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Endogenous ligand for the apelin receptor (APLNR) (PubMed:10525157). Drives internalization of the apelin receptor (By similarity). Apelin-36 dissociates more hardly than (pyroglu)apelin-13 from APLNR (By similarity). Hormone involved in the regulation of cardiac precursor cell movements during gastrulation and heart morphogenesis (By similarity). Has an inhibitory effect on cytokine production in response to T-cell receptor/CD3 cross-linking; the oral intake of apelin in the colostrum and the milk might therefore modulate immune responses in neonates (By similarity). Plays a role in early coronary blood vessels formation (By similarity). Mediates myocardial contractility in an ERK1/2-dependent manner (By similarity). May also have a role in the central control of body fluid homeostasis by influencing vasopressin release and drinking behavior (By similarity).
Gene Details:
apelin
Host:
Rabbit
Immunogen:
Peptide sequence from Human Apelin protein
Isotype:
IgG
Protein Details:
Apelin
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody