ADA Antibody
Product Sizes
50ug
£305.00
OACA02537-50UG
100ug
£463.00
OACA02537-100UG
About this Product
- SKU:
- OACA02537
- Additional Names:
- ADA1;adenosine aminohydrolase;adenosine deaminase.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine (PubMed:8452534; PubMed:16670267). Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine; and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation; by binding DPP4 (PubMed:20959412). Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (PubMed:11772392). Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion (By similarity). Enhances CD4+ T-cell differentiation and proliferation (PubMed:20959412). Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A; by enhancing their ligand affinity via conformational change (PubMed:23193172). Stimulates plasminogen activation (PubMed:15016824). Plays a role in male fertility (PubMed:21919946; PubMed:26166670). Plays a protective role in early postimplantation embryonic development (By similarity).
- Gene Details:
- adenosine deaminase
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Adenosine deaminase protein (157-343AA)
- Isotype:
- IgG
- Protein Details:
- Adenosine deaminase
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
