CHD1 Antibody
Product Sizes
100ul
£500.00
OACA02431-100UL
About this Product
- SKU:
- OACA02431
- Additional Names:
- ATP-dependent helicase CHD1;CHD-1;chromodomain-helicase-DNA-binding protein 1;PILBOS.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- Varies by lot. See vial for concentration.
- Extra Details:
- ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I; and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling; but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2; the FACT complex; the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3 (PubMed:18042460; PubMed:28866611). Required for maintaining open chromatin and pluripotency in embryonic stem cells (By similarity).
- Gene Details:
- chromodomain helicase DNA binding protein 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Chromodomain-helicase-DNA-binding protein 1 protein (1501-1710AA)
- Isotype:
- IgG
- Molecular Weight:
- 197 kDa
- Protein Details:
- Chromodomain-helicase-DNA-binding protein 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
