KNG1 Antibody - FITC Conjugated
Product Sizes
100ug
£478.00
OACA02009-100UG
About this Product
- SKU:
- OACA02009
- Additional Names:
- alpha-2-thiol proteinase inhibitor;BDK;BK;bradykinin;fitzgerald factor;HAE6;high molecular weight kininogen;HMWK;kininogen-1;KNG;williams-Fitzgerald-Flaujeac factor.
- Clonality:
- Polyclonal
- Conjugate:
- FITC
- Extra Details:
- (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction; (4B) induction of hypotension; (4C) natriuresis and diuresis; (4D) decrease in blood glucose level; (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability; (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins); (4F) it has a cardioprotective effect (directly via bradykinin action; indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
- Gene Details:
- kininogen 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Kininogen-1 protein (390-644AA)
- Isotype:
- IgG
- Protein Details:
- Kininogen-1
- Purity:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
