GDF15 Antibody - Biotin Conjugated
Product Sizes
100ug
£478.00
OACA01687-100UG
About this Product
- SKU:
- OACA01687
- Additional Names:
- GDF-15;growth/differentiation factor 15;macrophage inhibitory cytokine 1;MIC1;MIC-1;NAG-1;non-steroidal anti-inflammatory drug-activated gene-1;NRG-1;NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1;NSAID-activated gene 1 protein;NSAID-regulated gene 1 protein;PDF;PLAB;placental bone morphogenetic protein;placental TGF-beta;prostate differentiation factor;PTGFB;PTGF-beta.
- Clonality:
- Polyclonal
- Conjugate:
- Biotin
- Extra Details:
- Regulates food intake; energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886; PubMed:28846097; PubMed:28846098; PubMed:28846099; PubMed:23468844; PubMed:29046435). Binds to its receptor; GFRAL; and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886; PubMed:28846097; PubMed:28846098; PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala; which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes; inhibits growth hormone signaling (By similarity).
- Gene Details:
- growth differentiation factor 15
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Growth/differentiation factor 15 protein (198-308AA)
- Isotype:
- IgG
- Protein Details:
- Growth/differentiation factor 15
- Purity:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
