ARHGDIA Antibody
Product Sizes
100ug
£478.00
OACA00078-100UG
About this Product
- SKU:
- OACA00078
- Additional Names:
- epididymis secretory sperm binding protein Li 47e;GDIA1;GDP-dissociation inhibitor; aplysia RAS-related 1;HEL-S-47e;NPHS8;Rho GDP dissociation inhibitor (GDI) alpha;rho GDP-dissociation inhibitor 1;RHOGDI;Rho-GDI alpha;RHOGDI-1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them; and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42; RAC1 and RHOA in an inactive cytosolic pool; regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell; mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins; may play a role in cell motility regulation. In glioma cells; inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1.
- Gene Details:
- Rho GDP dissociation inhibitor alpha
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Rho GDP-dissociation inhibitor 1 protein (2-204AA)
- Isotype:
- IgG
- Protein Details:
- Rho GDP-dissociation inhibitor 1
- Purity:
- > 95% by Caprylic Acid Ammonium Sulfate Precipitation
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
