ADGRE1 Antibody
Product Sizes
100 ul
£576.00
OABF01779-100UL
About this Product
- SKU:
- OABF01779
- Additional Names:
- EMR1; TM7LN3
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1ug/ul
- Extra Details:
- The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors; which includes CD97; EMR1 (EGF-like molecule containing mucin-like hormone receptor 1; designated F4/80 in mouse); EMR2; EMR3; FIRE; and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains; and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1;3;4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues; including Kupffer cells in liver; splenic red pulp macrophages; brain microglia; gut lamina propria; and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5;6). The function of F4/80/EMR1 is unclear; but it is speculated to be involved in macrophage adhesion events; cell migration; or as a G-protein coupled signaling component of macrophages.
- Gene Details:
- adhesion G protein-coupled receptor E1
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from human EMR1
- Isotype:
- IgG
- Purification:
- Purified by Protein A.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C for 12 months.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
