AIM2 Antibody
Product Sizes
100ul
£597.00
OABF01632-100UL
About this Product
- SKU:
- OABF01632
- Additional Names:
- Gm1313;Ifi2;ifi-210;Ifi210;interferon-inducible protein 210;interferon-inducible protein AIM2;interferon-inducible protein p210.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 ug/ul
- Extra Details:
- Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent; caspase-1-independent cell death that involves caspase-8.
- Gene Details:
- absent in melanoma 2
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from mouse AIM2
- Isotype:
- IgG
- Protein Details:
- Interferon-inducible protein AIM2
- Purification:
- Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
