IFNAR1 Antibody
Product Sizes
100ul
£597.00
OABF01569-100UL
About this Product
- SKU:
- OABF01569
- Additional Names:
- alpha-type antiviral protein;AVP;beta-type antiviral protein;CRF2-1;cytokine receptor class-II member 1;cytokine receptor family 2 member 1;IFNalpha/beta receptor 1;IFN-alpha/beta receptor 1;IFN-alpha-REC;IFNAR;IFNBR;IFN-R-1;IFRC;interferon (alpha; beta and omega) receptor 1;interferon alpha/beta receptor 1;interferon receptor 1;interferon-alpha/beta receptor alpha chain;interferon-beta receptor 1;type I interferon receptor 1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 ug/ul
- Extra Details:
- Component of the receptor for type I interferons; including interferons alpha; IFNB1 and IFNW1 (PubMed:2153461; PubMed:7665574; PubMed:10049744; PubMed:14532120; PubMed:15337770; PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574; PubMed:10049744; PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade; and triggers tyrosine phosphorylation of a number of proteins including JAKs; TYK2; STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574; PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).
- Gene Details:
- interferon alpha and beta receptor subunit 1
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic phosphopeptide derived from human IFNAR1 around the phosphorylation site of Ser535+Ser538
- Isotype:
- IgG
- Protein Details:
- Interferon alpha/beta receptor 1
- Purification:
- Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
