ATG16L1 Antibody
Product Sizes
100ul
£597.00
OABF01536-100UL
About this Product
- SKU:
- OABF01536
- Additional Names:
- APG16L;APG16L beta;APG16-like 1;ATG16 autophagy related 16-like 1;ATG16A;ATG16L;autophagy-related protein 16-1;IBD10;WD repeat domain 30;WDR30.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 ug/ul
- Extra Details:
- Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A; MAP1LC3B or MAP1LC3C); to produce a membrane-bound activated form of LC3 named LC3-II. Thereby; controls the elongation of the nascent autophagosomal membrane (PubMed:24553140; PubMed:23376921; PubMed:24954904; PubMed:27273576; PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (PubMed:25645662). Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340). Instead; promotes with NOD2 an autophagy-dependent antibacterial pathway (PubMed:20637199). Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966).
- Gene Details:
- autophagy related 16 like 1
- Host:
- Rabbit
- Immunogen:
- KLH conjugated Synthesised phosphopeptide derived from human ATG16A/ATG16L1 around the phosphorylation site of Ser287
- Isotype:
- IgG
- Protein Details:
- Autophagy-related protein 16-1
- Purification:
- Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
