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Antibodies

BCL2 Antibody

Product Sizes
100ul
£597.00
OABF01453-100UL
About this Product
SKU:
OABF01453
Additional Names:
apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1; regulatory subunit 50.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
1 ug/ul
Extra Details:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation; hence CASP1 activation and IL1B release (PubMed:17418785).
Gene Details:
BCL2 apoptosis regulator
Host:
Rabbit
Immunogen:
KLH conjugated synthetic peptide derived from human Bcl-2
Isotype:
IgG
Protein Details:
Apoptosis regulator Bcl-2
Purification:
Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody