ADAMTS5 Antibody
Product Sizes
100ul
£597.00
OABF01268-100UL
About this Product
- SKU:
- OABF01268
- Additional Names:
- a disintegrin and metalloproteinase with thrombospondin motifs 11;A disintegrin and metalloproteinase with thrombospondin motifs 5;a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; 5 (aggrecanase-2);ADAM-TS 11;ADAM-TS 5;ADAMTS11;ADAMTS-11;ADAMTS-5;ADAM-TS5;ADMP-2;aggrecanase-2.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 ug/ul
- Extra Details:
- Metalloproteinase that plays an important role in connective tissue organization; development; inflammation; arthritis; and cell migration. ADAMTS5 is an extracellular matrix (ECM) degrading enzyme that show proteolytic activity toward the hyalectan group of chondroitin sulfate proteoglycans (CSPGs) including aggrecan; versican; brevican and neurocan (PubMed:16133547; PubMed:18992360). Cleavage within the hyalectans occurs at Glu-Xaa recognition motifs. Plays a role in embryonic development; including limb and cardiac morphogenesis; and skeletal muscle development through its versican remodeling properties. Participates in development of brown adipose tissue and browning of white adipose tissue. Plays an important role for T-lymphocyte migration from draining lymph nodes following viral infection.
- Gene Details:
- ADAM metallopeptidase with thrombospondin type 1 motif 5
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from human ADAMTS5
- Isotype:
- IgG
- Protein Details:
- A disintegrin and metalloproteinase with thrombospondin motifs 5
- Purification:
- Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
