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Antibodies

CD44 Antibody

Product Sizes
100ul
£597.00
OABF01002-100UL
About this Product
SKU:
OABF01002
Additional Names:
CD44 antigen;CDW44;cell surface glycoprotein CD44;chondroitin sulfate proteoglycan 8;CSPG8;ECMR-III;epican;extracellular matrix receptor III;GP90 lymphocyte homing/adhesion receptor;HCELL;hematopoietic cell E- and L-selectin ligand;heparan sulfate proteoglycan;Hermes antigen;homing function and Indian blood group system;HUTCH-I;hyaluronate receptor;IN;Indian blood group antigen;LHR;MC56;MDU2;MDU3;MIC4;Pgp1;phagocytic glycoprotein 1;Phagocytic glycoprotein I;soluble CD44.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
1 ug/ul
Extra Details:
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA; and possibly also through its affinity for other ligands such as osteopontin; collagens; and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration; tumor growth and progression. In cancer cells; may play an important role in invadopodia formation. Also involved in lymphocyte activation; recirculation and homing; and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter; leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
Gene Details:
CD44 molecule (Indian blood group)
Host:
Rabbit
Immunogen:
KLH conjugated synthetic peptide derived from human CD44
Isotype:
IgG
Protein Details:
CD44 antigen
Purification:
Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody