MKI67 Antibody
Product Sizes
100ul
£597.00
OABF00917-100UL
About this Product
- SKU:
- OABF00917
- Additional Names:
- antigen identified by monoclonal antibody Ki-67;antigen Ki67;KIA;MIB-;MIB-1;Molecular Immunology Borstel antibody 1;PPP1R105;proliferation marker protein Ki-67;proliferation-related Ki-67 antigen;protein phosphatase 1; regulatory subunit 105.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 ug/ul
- Extra Details:
- Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome; the perichromosomal layer; and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant; dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA; with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
- Gene Details:
- marker of proliferation Ki-67
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from human Ki67
- Isotype:
- IgG
- Protein Details:
- Proliferation marker protein Ki-67
- Purification:
- Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
