SUMO1 Antibody
Product Sizes
100ul
£597.00
OABF00729-100UL
About this Product
- SKU:
- OABF00729
- Additional Names:
- DAP1;GAP modifying protein 1;GAP-modifying protein 1;GMP1;OFC10;PIC1;SENP2;sentrin;small ubiquitin-related modifier 1;SMT3;SMT3 homolog 3;SMT3 suppressor of mif two 3 homolog 1;SMT3C;SMT3H3;ubiquitin-homology domain protein PIC1;ubiquitin-like protein SMT3C;ubiquitin-like protein UBL1;UBL1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 ug/ul
- Extra Details:
- Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I; and can be promoted by E3 ligases such as PIAS1-4; RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport; DNA replication and repair; mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1 (PubMed:19223394). Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development. Covalently attached to ZFHX3 (PubMed:24651376).
- Gene Details:
- small ubiquitin like modifier 1
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from human SUMO 1
- Isotype:
- IgG
- Protein Details:
- Small ubiquitin-related modifier 1
- Purification:
- Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
