Fc gamma receptor III Recombinant Antibody [3G8]
Product Sizes
200 ug
£745.00
OAAV00887-200UG
About this Product
- SKU:
- OAAV00887
- Additional Names:
- ALPS1A;APO-1;Apo-1 antigen;APO-1 cell surface antigen;apoptosis antigen 1;apoptosis signaling receptor FAS;apoptosis-mediating surface antigen FAS;APT1;CD95;CD95 antigen;Fas (TNF receptor superfamily; member 6);Fas AMA;FAS1;FASLG receptor;FASTM;mutant tumor necrosis receptor superfamily member 6;TNF receptor superfamily member 6;TNFRSF6;tumor necrosis factor receptor superfamily member 6;tumor necrosis factor receptor superfamily; member 6.
- translate.label.attr.clone:
- R-125224
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format; for improved compatibility with existing reagents; assays and techniques.
- Gene Details:
- Fas cell surface death receptor
- Host:
- Rabbit
- Immunogen:
- R-125224 is generated by the humanization of the murine HFE7A anti-Fas antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas or the L5178YA1 cell line expressing murine Fas; but not to the parental WR19L or L5178Y cells.
- Isotype:
- IgG; kappa
- Protein Details:
- Tumor necrosis factor receptor superfamily member 6
- Purification:
- Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for up to 3 months. For longer storage; aliquot and store at -20C.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
