Human BLNK Antibody : PE
Product Sizes
10 Tests
£218.00
OAAQ00172-10TESTS
100 Tests
£457.00
OAAQ00172-100TESTS
About this Product
- SKU:
- OAAQ00172
- Additional Names:
- bca; AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65
- translate.label.attr.clone:
- BLNKY84-H4
- Clonality:
- Monoclonal
- Conjugate:
- PE: Phycoerythrin
- Extra Details:
- This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways; thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells; a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.
- Gene Details:
- B cell linker
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Tyr84 of human phospho BLNK
- Isotype:
- Rabbit IgG1k
- Protein Details:
- B-cell linker protein
- Purification:
- Protein A+G
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
