Human TP53 Antibody : APC
Product Sizes
10 Tests
£218.00
OAAQ00039-10TESTS
100 Tests
£457.00
OAAQ00039-100TESTS
About this Product
- SKU:
- OAAQ00039
- Additional Names:
- P53; BCC7; LFS1; BMFS5; TRP53
- translate.label.attr.clone:
- P53S15-1C11
- Clonality:
- Monoclonal
- Conjugate:
- APC: Allophycocyanin
- Extra Details:
- This gene encodes a tumor suppressor protein containing transcriptional activation; DNA binding; and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes; thereby inducing cell cycle arrest; apoptosis; senescence; DNA repair; or changes in metabolism. Mutations in this gene are associated with a variety of human cancers; including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546; 20937277).
- Gene Details:
- tumor protein p53
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Ser15 of human phospho p53.
- Isotype:
- Rabbit IgG1k
- Protein Details:
- cellular tumor antigen p53
- Purification:
- Protein A+G
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
