Human STAT6 Antibody : SureLight 488
Product Sizes
10 Tests
£218.00
OAAQ00018-10TESTS
100 Tests
£457.00
OAAQ00018-100TESTS
About this Product
- SKU:
- OAAQ00018
- Additional Names:
- STAT6B; STAT6C; D12S1644; IL-4-STAT
- translate.label.attr.clone:
- Stat6Y641-G12
- Clonality:
- Monoclonal
- Conjugate:
- SureLight 488
- Extra Details:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors; STAT family members are phosphorylated by the receptor associated kinases; and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L); which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells; expression of cell surface markers; and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
- Gene Details:
- signal transducer and activator of transcription 6
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Tyr641 of human phospho Stat6
- Isotype:
- Rabbit IgG1k
- Protein Details:
- signal transducer and activator of transcription 6
- Purification:
- Protein A+G
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
