BNIP3L Antibody
Product Sizes
50ul
£264.00
OAAN03559-50UL
100ul
£379.00
OAAN03559-100UL
200ul
£581.00
OAAN03559-200UL
About this Product
- SKU:
- OAAN03559
- Additional Names:
- NIX; BNIP3a
- Clonality:
- Polyclonal
- Extra Details:
- Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL; although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage; participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP; BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
- Gene Details:
- BCL2 interacting protein 3 like
- Host:
- Rabbit
- Immunogen:
- Recombinant Protein
- Isotype:
- IgG
- Molecular Weight:
- 24 kDa
- Protein Details:
- Tumor necrosis factor receptor superfamily member 10A
- Purification:
- Affinity purification
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquote and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
