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Antibodies

HCFC1 Antibody

Product Sizes
50ul
£264.00
OAAN03260-50UL
100ul
£379.00
OAAN03260-100UL
200ul
£581.00
OAAN03260-200UL
About this Product
SKU:
OAAN03260
Additional Names:
CFF; HCF; HCF1; HFC1; MRX3; VCAF; HCF-1; PPP1R89
Clonality:
Polyclonal
Extra Details:
Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription; respectively) together. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. In case of human herpes simplex virus (HSV) infection; HCFC1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and POU2F1 thereby enabling the transcription of the viral immediate early genes.
Gene Details:
host cell factor C1
Host:
Rabbit
Immunogen:
Recombinant Protein
Isotype:
IgG
Molecular Weight:
209 kDa
Protein Details:
Glycophorin-A
Purification:
Affinity purification
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at +4C. For long term storage; aliquote and store at -20C. Avoid freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody