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Antibodies

MGMT Antibody

Product Sizes
50ul
£264.00
OAAN03168-50UL
100ul
£379.00
OAAN03168-100UL
200ul
£581.00
OAAN03168-200UL
About this Product
SKU:
OAAN03168
Additional Names:
6-O-methylguanine-DNA methyltransferase; Methylated-DNA--protein-cysteine methyltransferase; O-6-methylguanine-DNA-alkyltransferase
Clonality:
Polyclonal
Extra Details:
Alkylating agents are potent carcinogens that can result in cell death; mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule; which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types; including colorectal cancer; lung cancer; lymphoma and glioblastoma.
Gene Details:
O-6-methylguanine-DNA methyltransferase
Host:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human MGMT.
Isotype:
IgG
Molecular Weight:
22 kDa
Protein Details:
Endothelin-1
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody