ALOX5 Antibody
Product Sizes
50ul
£321.00
OAAN03114-50UL
100ul
£479.00
OAAN03114-100UL
200ul
£708.00
OAAN03114-200UL
About this Product
- SKU:
- OAAN03114
- Additional Names:
- 5-LO; 5LPG; LOG5; 5-LOX
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein; which is expressed specifically in bone marrow-derived cells; catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8;11;14-cis-eicosatetraenoic acid; and further to the allylic epoxide 5(S)-trans-7;9-trans-11;14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- arachidonate 5-lipoxygenase
- Host:
- Rabbit
- Immunogen:
- A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Ser271 of human ALOX5
- Isotype:
- IgG
- Molecular Weight:
- 78 kDa
- Protein Details:
- Arachidonate 5-lipoxygenase
- Purification:
- Affinity purified against immunogen
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
