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Antibodies

RB1 Antibody

Product Sizes
50ul
£321.00
OAAN03077-50UL
100ul
£479.00
OAAN03077-100UL
200ul
£708.00
OAAN03077-200UL
About this Product
SKU:
OAAN03077
Additional Names:
RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active; hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB); bladder cancer; and osteogenic sarcoma.
Gene Details:
retinoblastoma 1
Host:
Rabbit
Immunogen:
A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Ser780 of human RB1
Isotype:
IgG
Molecular Weight:
110 kDa
Protein Details:
Retinoblastoma-associated protein
Purification:
Affinity purified against immunogen
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody