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Antibodies

CAD Antibody

Product Sizes
50ul
£264.00
OAAN02691-50UL
100ul
£379.00
OAAN02691-100UL
200ul
£581.00
OAAN02691-200UL
About this Product
SKU:
OAAN02691
Additional Names:
CDG1Z; DEE50; GATD4; EIEE50
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II); aspartate transcarbamoylase; and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade; which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Details:
carbamoyl-phosphate synthetase 2; aspartate transcarbamylase; and dihydroorotase
Host:
Rabbit
Immunogen:
Recombinant protein of human CAD
Isotype:
IgG
Molecular Weight:
243 kDa
Protein Details:
CAD protein
Purification:
Affinity purified against immunogen
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody