APITD1 Antibody
Product Sizes
50ul
£264.00
OAAN02667-50UL
100ul
£379.00
OAAN02667-100UL
200ul
£581.00
OAAN02667-200UL
About this Product
- SKU:
- OAAN02667
- Additional Names:
- MHF1; APITD1; CENP-S; FAAP16
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain; similar to that found in TATA box-binding protein-associated factor; TAF(II)31; which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors; and was shown to reduce cell growth in neuroblastoma cells; suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes; including the Fanconi anemia (FA) core complex; the APITD1/CENPS complex; and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex; and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene; as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7.
- Gene Details:
- apoptosis-inducing; TAF9-like domain 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human APITD1
- Isotype:
- IgG
- Molecular Weight:
- 16 kDa
- Protein Details:
- Centromere protein S
- Purification:
- Affinity purified against immunogen
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
