C5 Antibody
Product Sizes
50ul
£264.00
OAAN02597-50UL
100ul
£379.00
OAAN02597-100UL
200ul
£581.00
OAAN02597-200UL
About this Product
- SKU:
- OAAN02597
- Additional Names:
- C5D; C5a; C5b; ECLZB; CPAMD4
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- This gene encodes a component of the complement system; a part of the innate immune system that plays an important role in inflammation; host homeostasis; and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products; including the C5 alpha chain; C5 beta chain; C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains; which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin; which possesses potent spasmogenic and chemotactic activity; and the C5b macromolecular cleavage product; a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency; a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
- Gene Details:
- complement component 5
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human C5
- Isotype:
- IgG
- Molecular Weight:
- 188 kDa
- Protein Details:
- Complement C5
- Purification:
- Affinity purified against immunogen
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
