CHRFAM7A Antibody
Product Sizes
50ul
£264.00
OAAN02465-50UL
100ul
£379.00
OAAN02465-100UL
200ul
£581.00
OAAN02465-200UL
About this Product
- SKU:
- OAAN02465
- Additional Names:
- D-10; CHRNA7; NACHRA7; CHRNA7-DR1
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7; which is located on chromosome 15 in a region associated with several neuropsychiatric disorders; is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed; and two variants exist; for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene; translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
- Gene Details:
- CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CHRFAM7A (NP_647536.1).
- Isotype:
- IgG
- Molecular Weight:
- 46 kDa
- Protein Details:
- CHRNA7-FAM7A fusion protein
- Purification:
- Affinity purified against immunogen
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20°C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
