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Antibodies

ATP6V1B1 Antibody

Product Sizes
50ul
£264.00
OAAN02034-50UL
100ul
£379.00
OAAN02034-100UL
200ul
£581.00
OAAN02034-200UL
About this Product
SKU:
OAAN02034
Additional Names:
VATB; VMA2; VPP3; DRTA2; RTA1B; ATP6B1
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
This gene encodes a component of vacuolar ATPase (V-ATPase); a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting; zymogen activation; receptor-mediated endocytosis; and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits; two G subunits plus the C; D; E; F; and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a; c; c'; c''; and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.
Gene Details:
ATPase H+ transporting V1 subunit B1
Host:
Rabbit
Immunogen:
Recombinant protein of human ATP6V1B1
Isotype:
IgG
Molecular Weight:
57 kDa
Protein Details:
V-type proton ATPase subunit B; kidney isoform
Purification:
Affinity purified against immunogen
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody