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Antibodies

BAP1 Antibody

Product Sizes
50ul
£264.00
OAAN01859-50UL
100ul
£379.00
OAAN01859-100UL
200ul
£581.00
OAAN01859-200UL
About this Product
SKU:
OAAN01859
Additional Names:
UCHL2; hucep-6; HUCEP-13
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition; the enzyme may be involved in regulation of transcription; regulation of cell cycle and growth; response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS); which involves increased risk of cancers including malignant mesothelioma; uveal melanoma and cutaneous melanoma.
Gene Details:
BRCA1 associated protein 1
Host:
Rabbit
Immunogen:
Recombinant protein of human BAP1
Isotype:
IgG
Molecular Weight:
80 kDa
Protein Details:
Ubiquitin carboxyl-terminal hydrolase BAP1
Purification:
Affinity purified against immunogen
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody