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Antibodies

ANTXR1 Antibody

Product Sizes
50ul
£264.00
OAAN01854-50UL
100ul
£379.00
OAAN01854-100UL
200ul
£581.00
OAAN01854-200UL
About this Product
SKU:
OAAN01854
Additional Names:
ATR; GAPO; TEM8
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin; the causative agent of the disease; anthrax. The binding of the protective antigen (PA) component; of the tripartite anthrax toxin; to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell; the other two components of anthrax toxin; edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
Gene Details:
anthrax toxin receptor 1
Host:
Rabbit
Immunogen:
Recombinant protein of human ANTXR1
Isotype:
IgG
Molecular Weight:
63 kDa
Protein Details:
Anthrax toxin receptor 1
Purification:
Affinity purified against immunogen
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody