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Antibodies

ALAS1 Antibody

Product Sizes
50ul
£264.00
OAAN01853-50UL
100ul
£379.00
OAAN01853-100UL
200ul
£581.00
OAAN01853-200UL
About this Product
SKU:
OAAN01853
Additional Names:
ALAS; MIG4; ALAS3; ALASH; ALAS-H
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Details:
5'-aminolevulinate synthase 1
Host:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALAS1 (NP_954635.1).
Isotype:
IgG
Molecular Weight:
71 kDa
Protein Details:
5-aminolevulinate synthase; nonspecific; mitochondrial
Purification:
Affinity purified against immunogen
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20°C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody